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1) NOVELTY and ORIGINALITY are of primary importance. The results presented must significantly advance the field and improve scientific knowledge..

3) SIGNIFICANCE: Accounts of research must appeal to a broad readership. In the cover letter, authors should provide a paragraph explaining how the work differs from the knowledge available in the literature.

Manuscripts that do not satisfy these general requirements will not be sent out for peer review and will be returned to the authors.


All manuscripts will be first evaluated for adherence to submission guidelines, assessed by the editors, and may then undergo a peer-review process. Provisional or final acceptance is based on scope, originality, scientific accuracy, relevance, clarity, and topical balance of the Journal. Decisions will be communicated to the corresponding author by e-mail.


On e-mail (...........)

Manuscript Preparation

At first submission, manuscripts may be submitted as single Word or PDF files, including references, figure legends, figures, and tables. All manuscript components need to be included to allow for evaluation of your manuscript. Graphical Abstract and Highlight files are optional at initial submission. If the editors determine that the work is potentially publishable, source files of the manuscript, figures, and tables will be required as well as other submission elements such as permissions and the authorship agreement form (see below). Include a cover letter and title page with counts as specified below.

COVER LETTER: Be sure to state that the manuscript, or any part of it, has not been published and will not be submitted elsewhere for publication while being considered by the journal Nanomedicine: NBM in the cover letter. If there is any overlap between the submission and any other material, published or submitted, detail the nature of and reason for the overlap; as relevant, upload a copy of the other material.

TITLE PAGE: The title page should contain these elements: full title, all authors' names, academic degrees, and affiliations; short title (not to exceed 50 characters, including spaces); name and complete address for corresponding author and address for reprints if different from correspondence; fax and telephone number and e-mail address; word count for abstract; complete manuscript word count (including body text and figure legends, but excluding abstract, title page, and references), and number of figures/tables. There is no length limit on Supplementary Material. Manuscripts with over-the-limit word counts will be returned to the authors without further review.The title page must include statements of funding or conflicts of interest. Please make note of any prior presentation of abstracts at meetings regarding the research.

TITLE: A title should describe the article's content clearly and precisely and allow the reader to decide whether it would be appropriate to consult the article further. The title is the advertisement for the article; a poorly titled article may never reach its target audience, so be specific. Omit unnecessary words such as “Novel,” “New,” “A study of,” “Investigations of,” “Observations on,” etc. Do not use abbreviations and jargon. Avoid overinflated, bombastic “marketing” titles. Indexing and abstracting services depend on the accuracy of the title and keywords used in cross-referencing are extracted from the title itself.

ABSTRACT: A concise and factual summary of 150 words or less without internal subheadings is required. The abstract should state briefly the purpose of the research, the principal results, and major conclusions. An abstract is often presented separetely from the article, so it must be able to stand alone. For this reason, references and abbreviations should be avoided, but, if essential, they must be definted at their first mention in the abstract itself. Insert 3 to 5 key words after the abstract. Be sure to include the abstract in the manuscript file.

GRAPHICAL ABSTRACTS: If the work is determined to have potential for publication (i.e., the editorial decision is REVISE or ACCEPT, authors are required to submit a graphical abstract for their article containing one image and a short textual piece; both should briefly summarize the essence of the paper in a concise form designed to capture the attention of a wide readership and for compilation of databases. Graphical abstracts should be included as a separate file.

The image should present the key points of the paper in a concise, pictorial form designed to seize the attention of readers and should not contain more than four panels. Please submit one image (in .tif or .eps format). The text component should be ~50-100 words in .doc format, and it should not be the same as the abstract in the manuscript. If a figure in the manuscript is used as the graphical abstract image, please note this at the end of the abstract (i.e.: Graphical Abstract: Figure 2), and refer to the system's instructions for uploading.

TEXT: For Communications and Original Articles, the text should include the headings Background, Methods, Results, and Discussion. Only essential data and descriptions should be provided in the Methods and Results. All experimental details including synthetic and analytical procedures must be provided as SUPPLEMENTARY MATERIALS (see details below). All pages must be numbered. Abbreviations must be parenthetically notated at first mention in the text. Each table and figure must be mentioned in the text. Reports of studies on humans and animals must indicate that each study has been approved by an institutional review committee and the procedures followed are in accordance with institutional guidelines. Provide generic rather than trademarked names of drugs.

ACKNOWLEDGMENTS: The acknowledgments section recognizes substantive contributions of individuals who do not meet the criteria for authorship (see below). The Editorial Office must receive written, signed consent from each person recognized in the acknowledgments to be mentioned in the article because acknowledgment can imply endorsement of data and conclusions. (See a sample of an Acknowledgement.) Upload each permission separately in the online system. Do not include statements of funding, conflicts, or other disclosures in the Acknowledgments; these must appear on the title page.

REFERENCES: Cite references in numeric order according to the first mention in the text. Accuracy of reference data is the responsibility of the author. Verify all references against original sources. “In press” citations must have been accepted for publication and the name of the journal or book publisher must be included; these citations must be updated before publication. Unpublished results and personal communications should not appear in the reference list but may be mentioned in the text. Authors wishing to cite unpublished material must have a letter of permission from the originator of the communication to do so. This letter should be submitted with the manuscript.

References can be in any style or format as long as the style is consistent. Author(s) name(s), journal title/book title, article title, year of publication, volume and issue or book chapter and the pagination must be present. The reference style required by the journal will be applied to the published version by Elsevier.

For those who wish to format the references, if using EndNote software, the journal reference style is Embellished Vancouver (Style 3a). Reference format should conform to the examples shown below, and journal abbreviations should conform to the style used in the Cumulated Index Medicus.

The style of citation should be as follows:

Journals: authors' last names and initials; title of article; journal name; date; volume number, and inclusive pages (list all authors when six or fewer; when seven or more, list six and add et al):
1. Graeber GM, Gupta NC, Murray GF. Positron emission tomographic imaging with fluorodeoxyglucose is efficacious in evaluating malignant pulmonary disease. J Thorac Cardiovasc Surg 1999;117:719-27.
2. Lytle BW, Blackstone EH, Loop FD, Houghtaling PL, Arnold JH, Akhrass R, et al. Two internal thoracic artery grafts are better than one. J Thorac Cardiovasc Surg 1999;117:855-72.

Books: authors' last names and initials; chapter title, editor's name, book title, edition, city, publisher, date, and pages:

1. Mollnes TE. Analysis of in vivo complement activation: In: Herzenberg LA, Weir DM, Herzenberg LA, Blackwell C, editors. Weir's handbook of experimental immunology. Volume 78, 5th ed. Boston: Blackwell Science; 1997, p. 1-8.

FIGURES: Figures must be of professional quality and suitable for evaluation purposes. Be sure all font is at a readable size. When possible, please use first-generation artwork. If a revision is requested, source files must be provided: Figures must be submitted in electronic figure file format:.tif, .eps, or .jpg format. Figures may be black and white line art, graphs, halftones (photographs), or color. Line art (black lines on a white background) must have a minimum resolution of 1,000 ppi. Combination line art (eg, line art with gray fill patterns) must be created at 500 ppi. Black and white or color photographs must have a minimum resolution of 300 ppi.

Illustrations should be saved at the recommended resolution setting and sized as close to a column width (3 to 4 inches) as possible. Create figures in scale with each other to the extent possible. Avoid background gridlines and other formatting that do not convey information (eg, superfluous use of 3-dimensional formatting, background shadings). Use uniform lettering and sizing of all original artwork. As a general rule the lettering on the artwork should have a finished, printed size of 7 points. Smaller lettering will yield barely legible text. Recommended font choices include Arial, Helvetica, or Symbol. Labeling of multipart figures (eg, A, B, C...) should use capital letters only and should be done consistently, preferably using uppercase type (Arial, Helvetica or Universe, 11 or 12 points) in the lower-right corner of the figure. Avoid headings on the figure when possible. There is no charge for publication of color illustrations.

TABLES: Table numbers should be Arabic, followed by a period and a brief title. Upload each table as a separate file. Use same type size as in text where possible. Supply a brief heading for each column. Do not use vertical lines between columns. Use horizontal lines above and below the column headings and at the bottom of the table only. Use extra space to delineate sections within the table. Abbreviations used in the table must be defined in a footnote to the table. Indicate footnotes in this order:  .


Checklist for Manuscript Submission

__ Cover letter stating that the manuscript or any part of it has not and will not be submitted or published elsewhere (initial submission)
__ Suggestions for potential reviewers (initial submission)

__ Point-by-point response to reviewers and editors (revised submissions)
__ Graphical Abstract (text in .doc format; image in .eps, .tif, or .jpg format for revised submissions depending on article type) (revised submissions)

Manuscript (in .doc format for revised submissions):
__ Title page
__ Title of article
__ Full names(s), academic degree(s), affiliation(s) and titles of author(s)
__ Author to whom correspondence, proof, and reprint requests are to be sent, including address and business and home telephone numbers, fax number, and e-mail address
__ Any conflict of interest statement(s), disclosure(s), and/or financial support information, including donations
__ Word count for the abstract, a complete manuscript word count (to include body text and figure legends), number of references, and number of figures and/or tables
__ Abstract (double-spaced as part of manuscript file)
__ Article proper (double-spaced)
__ Acknowledgments, if any
__ References (double-spaced on a separate page of the manuscript file)
__ Figure legends (double-spaced on a separate page of the manuscript file)

__ Tables (uploaded separately as .doc files for revised submissions)
__ Figures (uploaded as separate files in .eps, .tif, or .jpg for revised submissions)
__ Supplementary Material and/or Videos, properly formatted (uploaded as separate files)

__ Signed permission to reproduce any previously published material, in all forms and media (scanned in as a file and uploaded as Permission)
__ Signed permission from person(s) named in Acknowledgments (scanned in as a file and uploaded as Permission)
__ Authorship agreement form (revised submissions)

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